Research Technique

Bioinformatics

Research Technique
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Research Technique

Using computers to store, organize, & analyze biological data. The exponential growth of data from next-gen sequencing has made bioinformatics essential to genetics research.

EXAMPLES: genome assembly, genetic variant detection, and sequence alignment.

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Bioinformatics i/ˌbaɪ.oʊˌɪnfərˈmætɪks/ is an interdisciplinary field that develops methods and software tools for understanding biological data. As an interdisciplinary field of science, bioinformatics combinescomputer science, statistics, mathematics, and engineering to analyze and interpret biological data. Bioinformatics has been used for in silico analyses of biological queries using mathematical and statistical techniques. Bioinformatics is both an […] read more

Genetic Analysis

Research Technique
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Research Technique

Generation and propagation of organisms of the same genetic strain, allowing production of populations of organisms with defined mutations: to study traits, and to understand biological systems.

EXAMPLES: inbreeding, genetic crosses, cell culture, and mutagenesis

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  Genetic analysis is the overall process of studying and researching in fields of science that involve genetics and molecular biology. There are a number of applications that are developed from this research, and these are also considered parts of the process. The base system of analysis revolves around general genetics. Basic studies include identification […] read more

Imaging

Research Technique
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Research Technique

The visual representation of an organism’s exterior and interior at different magnifications.


EXAMPLES: microscopy, radiography, fluorescent probes and biomarkers.

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Including: Microscopy is the technical field of using microscopes to view objects and areas of objects that cannot be seen with the naked eye (objects that are not within the resolution range of the normal eye). There are three well-known branches of microscopy: optical, electron, and scanning probe microscopy. Optical and electron microscopy involve the […] read more

Sequencing

Research Technique
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Research Technique

Determining the order of nucleotides of an DNA or RNA fragment. Sequencing may be applied to small and large amounts of nucleic acids, from a single gene to a whole genome.

EXAMPLES: Sanger Sequencing and Sequencing by Synthesis. Next generation sequencing techniques.

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DNA sequencing is the process of determining the precise order of nucleotides within a DNAmolecule. It includes any method or technology that is used to determine the order of the four bases—adenine, guanine, cytosine, and thymine—in a strand of DNA. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and […] read more

Molecular Genetics

Research Technique
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Research Technique

Lab methods that manipulate tissue, DNA, and protein to study the structure, function and interaction of genes.


Examples: extraction, cloning and amplification of RNA and DNA, gene knockdown and mutagenesis.

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Molecular genetics is the field of biology and genetics that studies the structure and function of genes at a molecular level. The study ofchromosomes and gene expression of an organism can give insight into heredity, genetic variation, and mutations. This is useful in the study ofdevelopmental biology and in understanding and treating genetic diseases. (From: […] read more